LiveClinicalTrials.gov, FDA, PubMed and Medicare — read straight from the source.

Clinical answers, cited.
355 PharmaPulse tools behind one URL.
Frontier models: 100% correct with Pipeworx, 63% with web search

Ask what phase a trial is in, whether the FDA has flagged a safety signal, what a drug's label warns about, or whether Medicare will pay for it — and get the answer with the record it came from. Your agent reads the primary sources directly, so nothing depends on what it happened to memorise during training.

One connection · no per-source API keys · free to start

← All verticals

Included Packs

🧬
ClinicalTrials.gov

Search 400K+ clinical trials. Filter by phase, status, sponsor, condition. Track pipeline progress.

💊
OpenFDA

Drug adverse events (FAERS), FDA approvals, drug labels, recalls, safety signal detection.

💉
RxNorm

Drug name normalization (brand ↔ generic), drug interactions, NDC codes.

📄
SEC EDGAR

Pharma company financials, 10-K/10-Q filings, R&D spend, revenue, patent cliff disclosures.

📚
PubMed

Search 40M+ biomedical citations and research publications.

📋
Patents

Search patent filings for drug compounds, methods, formulations.

🧬
Genomics & Variants

BioThings (MyGene / MyVariant / MyDisease / MyChem), GWAS Catalog, Ensembl, gnomAD — gene, variant, and disease annotation.

🎗️
Cancer Genomics

NCI GDC and cBioPortal — cancer studies, cases, mutations, and genomic files across TCGA/TARGET/CPTAC.

🔬
Proteins & Structure

UniProt, AlphaFold, RCSB PDB, Human Protein Atlas, InterPro — sequences, 3D structures, expression, and domains.

🔁
Pathways & Reactions

KEGG, Reactome, WikiPathways, Rhea, QuickGO — metabolic/signaling pathways, biochemical reactions, and Gene Ontology.

🔗
Interactions & Targets

IntAct, STRING, Guide to PHARMACOLOGY — protein interactions and quantitative drug-target pharmacology.

⚗️
Chemistry

PubChem, ChEMBL, NCI CACTUS — compound properties, bioactivity, and chemical identifier resolution.

📊
Omics Datasets

Expression Atlas (transcriptomics), PRIDE (proteomics), MetaboLights (metabolomics) — the EBI omics trio.

🧫
Model Organisms & Literature

SGD (yeast), PomBase (fission yeast), Europe PMC, DailyMed, MedlinePlus — curated genetics and biomedical references.

Setup

1
Sign up for Pipeworx

Create a free account at /signup and grab your API key from /account.

2
Connect to Claude

Choose one of these options:

Option A — Claude on the web

Open claude.ai/customize/connectors, click Add custom connector, name it Pipeworx Pharma and paste this URL. Leave the OAuth client ID and secret blank — the connector registers itself.

connector URL
https://gateway.pipeworx.io/mcp?vertical=pharma

Then click Connect and sign in with GitHub. That step is free and takes you from 50 calls a day to 200 — same connection either way, and you can skip it and sign in later. In a new chat, open the tools menu and enable the connector.

Custom connectors need a paid Claude plan — that is an Anthropic gate, not a Pipeworx one.

Option B — Persistent MCP config

Add this to your claude_desktop_config.json:

claude_desktop_config.json
{
  "mcpServers": {
    "pipeworx-pharma": {
      "command": "npx",
      "args": [
        "-y",
        "mcp-remote",
        "https://gateway.pipeworx.io/mcp?vertical=pharma",
        "--header",
        "Authorization:Bearer YOUR_API_KEY"
      ]
    }
  }
}
Option C — Session only

Paste this into Claude to use for one conversation:

prompt
Use this MCP server for this conversation:

npx -y mcp-remote "https://gateway.pipeworx.io/mcp?vertical=pharma" --header "Authorization:Bearer YOUR_API_KEY"

Then search ClinicalTrials.gov for Phase 3 oncology trials.
3
No API keys needed

All data sources are free public APIs. Just sign up and start querying.

Tools

The clinical & competitive-intelligence core is listed below. This vertical also bundles the full research-bioinformatics layer — genomics, proteomics, protein structure, pathways, interactions, and chemistry (BioThings, KEGG, Reactome, UniProt, AlphaFold, ChEMBL, Guide to PHARMACOLOGY, Expression Atlas / PRIDE / MetaboLights, and more). Connect with ?vertical=pharma to get them all, or browse the full pack catalog.

ClinicalTrials.gov 5 tools

ct_searchSearch clinical trials by keyword, condition, or intervention
ct_get_studyGet detailed study record by NCT ID
ct_count_by_conditionCount trials by condition and phase
ct_sponsor_trialsList trials for a specific sponsor
ct_recent_updatesRecently updated or posted trials

OpenFDA 5 tools

fda_drug_eventsSearch adverse event reports (FAERS)
fda_drug_approvalsFDA drug approval history
fda_drug_labelsDrug labeling and package insert data
fda_drug_recallsDrug recall enforcement reports
fda_event_countsAggregate adverse event counts by drug or reaction

RxNorm 5 tools

rxnorm_searchSearch drugs by name (brand or generic)
rxnorm_get_propertiesGet drug properties and attributes
rxnorm_relatedFind related drugs (brand/generic mappings)
rxnorm_interactionsCheck drug-drug interactions
rxnorm_ndcLook up National Drug Code identifiers

SEC EDGAR 5 tools

edgar_search_filingsFull-text search across all SEC filings
edgar_company_filingsList filings for a specific company
edgar_company_factsAll XBRL facts for a company
edgar_company_conceptSingle XBRL concept time series
edgar_ticker_to_cikConvert ticker symbol to CIK number

PubMed 1 tool

search_pubmedSearch biomedical literature and citations

Patents 2 tools

search_patentsSearch patent filings by keyword or assignee
get_patentGet full patent details by number

FRED 2 tools

fred_get_seriesFetch time series observations
fred_searchSearch for economic data series

Common questions

What data sources are included in PharmaPulse?

ClinicalTrials.gov (active and completed trials by phase, sponsor, condition), OpenFDA (adverse events, drug approvals, label data), RxNorm (drug normalization, ingredient mapping), DailyMed (structured labels), SEC EDGAR (pharma company filings), and USPTO (patents and trademarks). Covers competitive intelligence, safety analysis, and clinical pipeline tracking.

Can I get a complete safety profile for a drug from one call?

Yes — the drug_safety_profile prompt and the pharma_drug_profile _intel tool fan out across RxNorm, OpenFDA adverse events, ClinicalTrials, and DailyMed in parallel. A query like "What are the side effects of Ozempic?" returns adverse event counts (54k+ reports for semaglutide), interaction warnings, and label sections in one round trip.

How do I track Phase 3 trials or competitive pipelines for a condition?

ClinicalTrials.gov tools let an agent filter trials by phase, status (recruiting, active, completed), condition, sponsor, and intervention type. Combine with EDGAR filings on the sponsor companies and USPTO patent search on the molecule for a full competitive-intelligence brief.

Is the drug data live or cached?

ClinicalTrials.gov updates are typically reflected within hours. OpenFDA adverse events are refreshed quarterly by FDA, with the most recent quarter usually 2–3 months behind. RxNorm releases monthly. Every response includes _meta.cache.fresh_until so agents can decide whether to refetch.