STRING-DB

liveBiologyScience

STRING — protein-protein interaction networks across ~12k organisms. Keyless.

5tools
0msauth
free tier50 calls/day

Tools

resolverequired: identifiers

Map free-text identifiers (gene symbols, accessions) → STRING identifiers.

Parameters
NameTypeDescription
identifiersreqarray—
speciesoptnumber—
limitoptnumber—
▶Try it
interactionsrequired: identifiers

Interaction partners for a set of proteins.

Parameters
NameTypeDescription
identifiersreqarray—
speciesoptnumber—
required_scoreoptnumber—
limitoptnumber—
network_typeoptstring—
▶Try it
networkrequired: identifiers

Network image url + tabular interaction data.

Parameters
NameTypeDescription
identifiersreqarray—
speciesoptnumber—
required_scoreoptnumber—
network_typeoptstring—
▶Try it
enrichmentrequired: identifiers

Functional enrichment (GO, KEGG, Pfam, Reactome, …) for a gene set.

Parameters
NameTypeDescription
identifiersreqarray—
speciesoptnumber—
▶Try it
homologyrequired: identifiers

Retrieve STRING-DB homology mappings for a list of protein identifiers (gene symbols or accessions) within a given NCBI taxonomy species (default 9606=human), returning cross-species homolog relations

Parameters
NameTypeDescription
identifiersreqarray—
speciesoptnumber—
▶Try it

Test with curl

The gateway speaks JSON-RPC 2.0 over HTTP POST. You can test any pack directly from the terminal.

List available tools
bash
curl -X POST https://gateway.pipeworx.io/string-db/mcp \
  -H "Content-Type: application/json" \
  -d '{"jsonrpc":"2.0","id":1,"method":"tools/list"}'
Call a tool
bash
curl -X POST https://gateway.pipeworx.io/string-db/mcp \
  -H "Content-Type: application/json" \
  -d '{"jsonrpc":"2.0","id":2,"method":"tools/call","params":{"name":"resolve","arguments":{"identifiers": "example"}}}'

Use with the SDK

Install @pipeworx/sdk to call tools from any TypeScript/Node project.

TypeScript
import { Pipeworx } from '@pipeworx/sdk';
const px = new Pipeworx();
const result = await px.call("resolve", {"identifiers":"example"});
ask_pipeworx
// Or ask in plain English:
const answer = await px.ask("string — protein-protein interaction networks across ~12k organisms");